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Technical Manager, UI · Sycamore Informatics

Lordson Vimal.

building clinical-trial platforms

I lead front-end engineering for regulated clinical-trial SaaS — the kind where an audit trail is a feature, not a log file.

Everything else here is mine: a learning platform that started with chess and didn't stop there.

See what I've built

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9yrs
shipping software
PBscale
clinical data platforms
6langs
used in production
3builds
side projects in flight

01 — About

  1. 2017 /3D & Render Pipelines
  2. 2020 /Clinical SaaS
  3. 2024 /Leading UI

I started in 3D visualization and render-pipeline automation — Unity, C#, Blender, Python — and ended up building software that pharmaceutical companies run clinical trials on. Since 2024 I’ve led UI at Sycamore Informatics: front-end architecture, distributed systems architecture, delivery, and the engineers who ship it. In practice I work as a full-stack engineer, designing and solving problems end to end.

What I actually care about is the craft — clean architecture, systems you can reason about, tooling that makes a team faster. That curiosity leaks into side projects: an interpreter for a language of my own, a code-graph server that feeds context to AI agents, and a chess platform that survives losing the network.

02 — What I do

Software that has to be right the first time

Pharmaceutical sponsors and CROs run trials on the software I build. Here, a mistake is a regulatory finding — so correctness, auditability, and traceability are daily engineering conversations, not afterthoughts.

// the systems we build

  • 01

    Protocol design

    study structure, visits, and assessments authored once

  • 02

    Metadata repositories

    governed standards, versioned and reusable across studies

  • 03

    Statistical computing

    validated environments for analysis and submission outputs

  • 04

    Data science workbench

    package management and reproducibility for research teams

21 CFR Part 11

Electronic records & signatures

Audit trails, e-signatures, immutable records, controlled access, and computer system validation (CSV / GAMP 5).

ICH E6 / GCP

Good Clinical Practice

ALCOA+ data integrity, end-to-end traceability, and controlled change across the trial lifecycle.

HIPAA

Protected health information

PHI handling, encryption at rest and in transit, least-privilege access, and BAAs.

Validated delivery

Engineering in a regulated environment

Documented requirements traceability, release validation, deviation handling, and SOC 2-aligned controls.

03 — The stack

Everything I reach for

50 elements · filter to isolate

  • Js JavaScript
  • Ts TypeScript
  • Go Go
  • Py Python
  • Rb Ruby
  • Sq SQL
  • Re React
  • So SolidJS
  • Tw Tailwind CSS v4
  • Wc Web Components
  • Sm State management
  • Ax Accessibility
  • Pf Performance & memory profiling
  • Nd Node.js
  • Ror Ruby on Rails
  • Nh Go (net/http)
  • Gr gRPC
  • Rst REST APIs
  • Gq GraphQL
  • Mb Message brokers
  • Pg PostgreSQL
  • Sl SQLite
  • Mei MeiliSearch
  • Aw AWS serverless (Lambda, autoscaling)
  • Pb Petabyte-scale storage
  • On Onion / clean architecture
  • Dd Domain-driven design
  • Ds Distributed SaaS
  • Ev Event-driven systems
  • Nx Monorepos (Nx)
  • Ad Architecture documentation
  • Ci Code review & CI quality gates
  • 11 21 CFR Part 11
  • E6 GCP / ICH E6
  • Hp HIPAA
  • G5 Computer system validation (GAMP 5)
  • Au Audit trails & e-signatures
  • Al ALCOA+ data integrity
  • Mcp Model Context Protocol (MCP)
  • Ag Agentic workflows & orchestration
  • Cx Context engineering & RAG
  • Llm LLM APIs & prompt design
  • Ca Coding agents in the loop
  • Ea Agent evals & guardrails
  • Un Unity
  • Bl Blender + Python scripting
  • Rn Procedural asset & render pipelines
  • Sd System design
  • Ai AI
  • Sa Static analysis & code-graph tooling

04 — Experience

201720192021202320252027
3D & Render Pipelines · House of Blue Beans
Clinical SaaS · Ephicacy
Leading UI · Sycamore Informatics

  1. Technical Manager, UI · Sycamore Informatics

    Nov 2024 – present

    Bangalore · ~300-person company

    Own front-end architecture, delivery, and the engineers, for validated clinical-trial products.

    • Architecture
    • Go
    • Mentoring
    • Lead front-end engineering for SaaS products used by pharmaceutical companies to run clinical trials, built to 21 CFR Part 11, GCP, and HIPAA requirements.
    • Own UI architecture, component systems, code quality, and delivery; drive requirements traceability and release validation with QA and Regulatory.
    • Contribute across the stack — APIs, data models, and services — on platforms that scale to petabytes of clinical data storage.
    • Grow and mentor the engineering team; hiring, 1:1s, and technical roadmap.
    Sycamore Informatics

  2. Frontend / Full-stack Engineer · Ephicacy

    Feb 2020 – Oct 2024

    Bangalore

    Built data-dense trial software end to end — React and TypeScript up front, Node and Python behind it.

    • React
    • TypeScript
    • Node.js
    • Performance
    • Built web applications for pharmaceutical clinical-trial data — capture, management, and reporting — to 21 CFR Part 11, GCP, and HIPAA standards.
    • Worked primarily in React and TypeScript on data-dense UIs, and across the stack in Node and Python on platforms scaling to petabytes of storage.
    • Drove front-end architecture, performance for large datasets, and code quality.
    Ephicacy

  3. Software Engineer · House of Blue Beans

    Feb 2017 – Oct 2019

    Bangalore · First company · ~50–100-person company

    Interior-design software in Unity, plus the Blender automation pipeline that rendered it.

    • Unity
    • C#
    • Blender
    • AWS
    • Built interior-design software with Unity and C#, backed by a Python service on an autoscaling AWS serverless architecture.
    • Developed 3D asset and rendering pipelines using Blender and Python.
    • Designed and built Trestle — an in-house automation tool (Python + Blender, Kivy desktop UI) that automated asset creation and rendering, saving several hundred person-hours every week.
    House of Blue Beans

05 — Projects

Three things I built for myself

01

Polyflow

In development

Code-flow analysis + MCP context server for AI agents

Indexes a whole codebase into a queryable graph — functions, routes, brokers, jobs, components, datastores — so AI coding agents can ask precise questions instead of grepping in circles.

5
languages parsed
4
edge protocols
n
repo fleet
  • Go
  • SQLite
  • MCP SDK
  • OTLP
› how it works
  • Parses Go, Ruby, Python, JavaScript, and TypeScript.
  • Cross-service edge inference (HTTP, brokers, gRPC, GraphQL) with static → candidate → verified confidence.
  • Runtime evidence fused from captured OTLP traces.
  • Multi-repo “fleet” support with federated querying; served over MCP, plus a web UI and CLI.

Static analysis, distributed-systems modelling, and AI-agent tooling in one box.

visit
polyflow indexed graph
02

ChessLeap

Live

Real-time online chess platform

Online multiplayer, a computer opponent across four difficulty tiers, and a solo analysis board — with a UI that survives losing the network.

4
engine tiers
3–60
min controls
0
moves lost offline
  • TypeScript
  • Real-time multiplayer
  • Google auth
› how it works
  • Blitz, rapid, and classical time controls (3–60 min) with increments.
  • Play, Train, and Learn sections.
  • Rated puzzles — each one carries a difficulty rating, so training scales with you.
  • Offline-tolerant UI — moves queue locally and sync on reconnect.

Real-time state sync, move validation, clock management, and engine integration in the browser.

visit
chessleap scholar's mate
03

ELV

Playable

A programming language, written from scratch

A high-level, dynamic, functional language built to understand how runtimes actually work. Lexer, parser, and evaluator all run in the browser — the REPL on its page is the real thing.

3
pipeline stages
4
primitive types
0
dependencies
  • TypeScript
  • Interpreter
  • In-browser REPL
› how it works
  • First-class functions and closures via nested def.
  • Primitives, var multi-assignment, for loops, if/else, unary & binary operators.
  • Distinct syntax — [ ] blocks, `## …
  • Lexer + recursive-descent parser + tree-walking interpreter in JavaScript.

A from-scratch language implementation, playable live on this site.

open
elv repl